منابع مشابه
Design and tests of an HIV vaccine.
It is likely that a successful vaccine against HIV will need to stimulate the innate immune system, generate high levels of neutralising antibody, strong cellular immune responses, and mucosal immunity. Early efforts to develop HIV vaccines attempted to use the virus glycoprotein, gp120, to induce neutralising antibody, but did not take into account the trimeric structure of the native glycopro...
متن کاملdesign of an analog fuzzy logic controller chip
fuzzy logic has been developed over the past three decades into a widely applied techinque in classification and control engineering. today fuzzy logic control is one of the most important applications of fuzzy set theory and specially fuzzy logic. there are two general approachs for using of fuzzy control, software and hardware. integrated circuits as a solution for hardware realization are us...
15 صفحه اولEpigraph: A Vaccine Design Tool Applied to an HIV Therapeutic Vaccine and a Pan-Filovirus Vaccine
Epigraph is an efficient graph-based algorithm for designing vaccine antigens to optimize potential T-cell epitope (PTE) coverage. Epigraph vaccine antigens are functionally similar to Mosaic vaccines, which have demonstrated effectiveness in preliminary HIV non-human primate studies. In contrast to the Mosaic algorithm, Epigraph is substantially faster, and in restricted cases, provides a math...
متن کاملAnti-Carbohydrate HIV Vaccine Design
R. Pantophlet (ed.), HIV Glycans in Infection and Immunity, DOI 10.1007/978-1-4614-8872-9_6, © Springer Science+Business Media New York 2014 Abstract HIV has evolved a number of strong defense mechanisms, including extensive glycosylation of its surface envelope glycoprotein, to evade host immune responses. Nevertheless, the discovery of a series of glycan-dependent broadly neutralizing antibod...
متن کاملdevelopment and implementation of an optimized control strategy for induction machine in an electric vehicle
in the area of automotive engineering there is a tendency to more electrification of power train. in this work control of an induction machine for the application of electric vehicle is investigated. through the changing operating point of the machine, adapting the rotor magnetization current seems to be useful to increase the machines efficiency. in the literature there are many approaches wh...
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ژورنال
عنوان ژورنال: British Medical Bulletin
سال: 2002
ISSN: 1471-8391,0007-1420
DOI: 10.1093/bmb/62.1.87